What is Basaloid neoplasm?
Basaloid tumors of the salivary glands are a heterogeneous group of benign and malignant lesions characterized by small tumor cells with round or ovoid nuclei surrounded by a thin rim of cytoplasm.
What is the process of making keratinocytes?
Keratinocytes are derived from undifferentiated cells in the stratum basale of the epidermis. The process of keratinization occurs in two stages, a synthetic stage and a degradative stage. The synthetic stage begins after the basal stem cells divide.
What are Trichoepitheliomas?
Trichoepithelioma is a rare benign skin lesion that originates from hair follicles. Trichoepitheliomas are mostly seen in the scalp, nose, forehead, and upper lip. These skin lesions originate from benign proliferation of epithelial-mesenchymal origin cells.
What is Basaloid proliferation?
Background: Basaloid epidermal proliferations, which histologically resemble basal cell carcinoma, have been described overlying dermatofibromas. Several etiologies have been proposed. Cutaneous myxomas are also benign mesynchymal tumors. Purpose: Basaloid proliferations have been noted overlying cutaneous myxomas.
What is the purpose of keratinocytes?
As the most dominant cell type constituting the epidermis, keratinocytes play multiple roles essential for skin repair. They are the executors of the re-epithelialization process, whereby keratinocytes migrate, proliferate, and differentiate to restore the epidermal barrier.
What is keratinocyte carcinoma?
For this reason, non-melanoma skin cancers such as basal cell carcinoma and squamous cell carcinoma are sometimes called keratinocyte cancers. The most common type of keratinocyte cancer is basal cell carcinoma. What Is Basal Cell Carcinoma? Basal cell carcinoma is a type of skin cancer.
What is basal cell carcinoma?
Basal cell carcinoma is a superficial, slowly growing papule or nodule that derives from certain epidermal cells. Basal cell carcinomas arise from keratinocytes near the basal layer and can be referred to as basaloid keratinocytes. Metastasis is rare, but local growth can be highly destructive.
How are basaloid tumours of the skin classified?
The basaloid tumours of the skin can be classified according to the general classification of skin tumours, including epidermal, appendageal (hair follicle and sweat gland derived) and others including cutaneous metastases.
What do keratinocytes do in the skin?
They make keratin, a protein that provides strength to skin, hair, and nails. Keratinocytes form in the deep, basal cell layer of the skin and gradually migrate upward, becoming squamous cells before reaching the surface of the skin over the course of a month.