What does Microglandular Hyperplasia mean?
Microglandular hyperplasia is a lesion of the uterine endocervical mucosa, often associated with a story of contraceptive drugs or pregnancy. It was frequently confused with adenocarcinoma or premalignant glandular changes until its benign nature was recognized.
Can squamous metaplasia become cancer?
Endocervical squamous metaplasia There is no risk of malignant transformation for squamous metaplasia. Nevertheless, the metaplastic change within the endocervix may increase the risk for human papilloma virus infection (Hwang et al., 2012), which is a risk factor for cervical cancer.
What does it mean by squamous metaplasia?
Squamous metaplasia is a benign non-cancerous change (metaplasia) of surfacing lining cells (epithelium) to a squamous morphology.
What is endocervical hyperplasia?
Histopathologically, lobular endocervical glandular hyperplasia is defined as benign hyperplastic glands arranged in a lobular pattern. They are often confused with minimal deviation adenocarcinoma, so-called adenoma malignum.
How is squamous metaplasia treated?
Conclusion: The therapeutic management of keratinizing squamous metaplasia is controversial, and currently no effective medical therapy is available for its treatment. Actually, patients undergo transurethral resections and a multidisciplinary approach is required to avoid cystectomy.
What is squamous metaplasia bladder?
Squamous metaplasia of the bladder is defined as the transformation of the normal urothelium into stratified squamous epithelium and can be either keratinizing or not. Nonkeratinizing squamous metaplasia (N-KSM) occurs normally in the trigone of the bladder.
How is an endocervical curettage performed?
A procedure done after an abnormal Pap test result in which a sample of tissue is scraped from the lining of the cervical canal (the inner part of the cervix that connects the uterus to the vagina) using a spoon-shaped instrument called a curette.
What is a squamous intraepithelial lesion?
Squamous intraepithelial lesions (SILs) are areas of abnormal tissue that may become cancerous. They’re usually the result of HPV but might not develop until long after you get the infection.
What is Microglandular?
Microglandular hyperplasia is a pseudoneoplastic proliferation of mucinous glands and stroma that tends to occur in response to progestational stimulation.
What does Adenosis mean?
(A-deh-NOH-sis) A disease or abnormal change in a gland. Breast adenosis is a benign condition in which the lobules are larger than usual.
What is Microglandular hyperplasia (MGH)?
Microglandular hyperplasia. Microglandular hyperplasia ( MGH) of the cervix is an epithelial ( endocervical mucosa) benign abnormality (lesion) associated with gland proliferation. It can terminate in mature squamous metaplasia, and it is suspected reserve cells are involved in this process, perhaps in the form of reserve cell hyperplasia
What is Microglandular hyperplasia of the uterus?
Microglandular Hyperplasia of Uterine Cervix. Microglandular Hyperplasia (MGH) of Uterine Cervix is a benign condition that occurs due to an abnormal increase of glands (endocervical glands) within the cervix.
What is squamous metaplasia of the bladder mucosa?
Introduction: Bladder mucosa is anatomically covered by urothelial epithelium. The replacement of the urothelium with stratified squamous cells is defined as squamous metaplasia which can be keratinizing or non-keratinizing.
Can cytomorphologic features of Microglandular hyperplasia be identified in cervical cytologic smears?
Objective: To identify cytomorphologic features specific to microglandular hyperplasia (MGH) in cervical cytologic smears. Study design: Twenty-four cervical smears from 24 patients obtained before the histologic diagnosis of MGH made on colposcopically directed biopsies during a period of two years (1995-1997) were evaluated.