Can januvia cause pancreatitis?
What is the most important information you should know about JANUVIA? JANUVIA can cause serious side effects, including: Inflammation of the pancreas (pancreatitis) which may be severe and lead to death. Certain medical problems make you more likely to get pancreatitis.
Why was januvia taken off the market?
Lawsuit documents reveal that doctors prescribed Januvia to the husband in 2007 to control his Type II diabetes symptoms to enjoy his day-to-day existence. He stopped taking the medication in October 2010 after learning he had been diagnosed with pancreatic cancer.
Is there a lawsuit against Januvia?
Judges consolidated lawsuits against the makers of Type 2 diabetes drugs Januvia, Janumet, Byetta and Victoza in California federal court. Nearly 1,000 plaintiffs claim the drugs caused pancreatic cancer and pancreatitis.
Can metformin cause acute pancreatitis?
Approximately 2% of cases of acute pancreatitis may be caused by drugs, but it is not a known complication of metformin therapy. To date only one case of pancreatitis has been reported in association with metformin, but that was secondary to metformin poisoning (overdose).
Does Januvia cause lactic acidosis?
Januvia and Janumet are similar medications used in the treatment of Type 2 diabetes. Common side effects include headache and flu-like symptoms. Some of the potential serious side effects include lactic acidosis, heart problems and pancreatitis.
Is Januvia bad for your liver?
Now, a new medical journal “To The Editor” letter suggests that Januvia may have a negative effect on the liver for certain patients, specifically “individuals with a history of nonalcoholic steatohepatitis or elevated hepatic enzymes”.
Is Januvia bad for your kidneys?
No clinical studies have linked the use of Januvia to kidney problems. But some people have reported kidney problems after taking Januvia, including kidney failure.
Does Januvia have a black box warning?
Januvia, a once-daily pill for type 2 diabetes (a DPP-4 inhibitor), has a new warning label for increased risk of heart failure. Though a recent outcome study showed clearly that Januvia is no riskier for the heart, the FDA seems to be taking a conservative approach based on other studies of similar drugs.
Is drug induced pancreatitis reversible?
1,2 Knowing which drugs are associated with acute pancreatic inflammation can help the hospitalist consider specific drugs as the cause within their differential diagnosis. Most cases of acute pancreatitis are reversible and resolve on their own within three to seven days after treatment begins.
Can metformin make pancreatitis worse?
Metformin is not generally known to cause or exacerbate pancreatitis, although cases of acute pancreatitis associated with metformin therapy have been reported in the literature. No cases involving chronic pancreatitis have been reported.
Should I stop taking Januvia If I have pancreatitis?
The FDA has not indicated that any users of Januvia or Janumet should stop taking their medication, and no medication (especially a diabetes drug) should be discontinued without the supervision of a physician. Any concerns about the potential for Januvia pancreatitis side effects should be reviewed with a doctor.
Can Januvia be discontinued?
The FDA has not indicated that any users of Januvia or Janumet should stop taking their medication, and no medication (especially a diabetes drug) should be discontinued without the supervision of a physician.
Why is the FDA recommending revisions to the prescribing information for pancreatitis?
Because acute pancreatitis is associated with considerable morbidity and mortality, and early recognition is important in reducing adverse health outcomes, FDA is recommending revisions to the prescribing information to alert healthcare professionals to this potentially serious adverse drug event.